TS. Trần Thị Thu Phương

Quá trình học tập, công tác

2010: Dược sĩ cao cấp Trường Đại học Dược Hà Nội

2013: Thạc sĩ Khoa học Dược. Trường Đại học Sư phạm Hà Nội

2017: Tiến sĩ Sinh học sức khoẻ – Viện nghiên cứu gen phân tử của Montpellier, Trung tâm nghiên cứu khoa học quốc gia, Lab adenovirus: thụ thể, vận chuyển và vec tơ. Trường đại học Monpellier 2

Hướng nghiên cứu

Đánh giá hoạt tính sinh học, đồng thời nghiên cứu cơ chế phân tử liên quan đến đáp ứng miễn dịch miễn dịch, ung thư và kháng viêm của các chất/ dịch chiết dẫn xuất từ dược liệu và các thuốc/ dạng bào chế khác.

Các công trình công bố

1. Tran Thi Thu Phuong1, Nguyen Hai Dang1,*, Nguyen Thi Hong Anh2, Do Hoang Giang2, Nguyen Tien Dat2,*. A new megastigmane glycoside and other constituents from Amomum muricarpum Elmer. Records of Natural Products-http://doi.org/10.25135/rnp.333.2203.2395
2. Tuan Hiep Tran#, TTPTran. Targeting the PD-1/PD-L1 axis for cancer treatment: a review on nanotechnology.  Royal Society Open Science. 2022 Apr 13;9(4):211991. doi: 10.1098/rsos.211991.
3. Minh Quang Pham, Duong Thi Bach Nguyen, TTP Tran. Pain relief after maxillofacical surgery : efficacy in patients undergoing ultrasound-guided trigeminal nerve block-a randomized controlled trial. Biomedical Research and Therapy. Vol 9 No 1 (2022) / 4865-4872
4. Karsten Eichholz, Tuan Hiep Tran, Coraline Chéneau, TTP Tran, Océane Paris, Martine Pugniere, and Eric Kremer. Adenovirus-α-defensin complexes induce NLRP3-associated maturation of human phagocytes via TLR4 engagement. Journal of virology. 2022 Jan 26 https://doi.org/10.1128/jvi.01850-21
5. TTP Tran#, Tuan Hiep Tran and Eric J Kremer. IgG-complexed adenovirus induce human plasmacytoid dendritic cell activation and apoptosis. Virus. 27 Aug 2021 13(9):1699. doi: 10.3390/v13091699.
6. Coraline Chéneau #, Karsten Eichholz#, Tuan Hiep Tran #, TTPT Tran  et al. Lactoferrin retargets human adenovirus to TLR4 to Induce an abortive NLRP3-asociated pyroptotic response in human phagocytes. Front. Immunol., 20 May 2021
7. TH Tran#, TTP Tran#, DH Truong et al. Toll-like receptor-targeted particles: A paradigm to manipulate the tumor microenvironment for cancer immunotherapy. Acta Biomater 2019 Aug, 94:82-96.
8. Dai Cao Phung, Hanh Thuy Nguyen, TTP Tran et al. Combined hyperhermia and chemotherapy as a synergistic anticancer treatment. Journal of pharmaceutical investigation. 6 March 2019
9. TTP Tran#, K Eichholz, P Amelio, et al. Humoral immune response to adenovirus induce tolerogenic dendritic cells that promote generation of regulatory T cells. Plos pathogens 2018 Aug 20;14(8)
10. HT Truong#, TTP Tran, HT Nguyen, et al. Modulating T-cell-based cancer immunotherapy via particulate systems. J Drug Targeting 2018 Jun 3:1-19.
11. TH Tran#, TTP Tran, HT Nguyen, et al. Nanoparticles for dendritic cell-based immunotherapy. International journal of pharmaceutics 2018; 542(1-2):253-265.
12. TH Tran#, Hanh Thuy Nguyen, Nam Van Le, TTP Tran et al. Engineering of multifunctional temperature-sénitive liposomes for synergistic photothermal, photodynamic, and chemotherapeutic effects. International journal of pharmaceutics, Vol 528, issue 1-2, page 692-704, 7 August 2017.
13. FJ Mennechet#, K Eichholz,  TTP Tran, Eric J. Immunité humorale anti-adénovirus Impact sur l’activation des cellules dendritiques Anti-adenovirus humoral immunity: impact on dendritic cell activation. Med Sci (Paris), Vol 33, No 6-7, Page 582-585 July 2017.
14. TH Tran#, Hanh Thuy Nguyen, TTP Tran et al.  Combined photothermal and photodynamic thẻapy by hyaluronic acid-decorated polyrrole nanoparticles. Nanomedicine, Vol 12, No 12, 2 Jun 2017.
15. K Eichholz#, T Bru, TTP Tran, et al. Immune-complexed adenoviruses induce AIM2-mediated pyroptosis in human dendritic cells. Plos pathogen 2016;12(9).
    FJ Mennechet#, TTP Tran, K Eichholz et al. Ebola virus vaccine: benefit and risks of adenovirus-based vectors. Expert review of vaccines, 2015. 14(11):1471-8.
16. MT Do#, HG Kim, TTP Tran, et al. Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression. Toxicology and Applied Pharmacology, 2014;280(1):138-48.
17. MT Do#, HG Kim, JH Choi, T Khanal, BH Park, TTP Tran, et al. Antitumor efficacy of piperine in the treatment of human HER2-overexpression brest cancer cells. Food Chem. 2013; 141(3):2591-9.
18. TTP Tran#, HG Kim, MK Na, HG Jeong. Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. Phytomedicine 2013;20(7):622-31.
19. HY Pil#, HG Kim, Choi JH, MT Do, TTP Tran, et al. 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea attenuates high glucose-induced hepatic lipogenesis in human HepG2 cells through activation of the liver kinase B1 and silent information regulator T1/AMPK-dependent pathway.Mol Nutr Food Res. ;57(3):471-82.
20. HG Kim#, EH Han, WS Jang, JH Choi, T Khanal, BH Park, TTP Tran, et al. Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages. Food Chem Toxicol. 2012 ;50(7):2342-8.
21. MT Do#, HG Kim, JH Choi, T Khanal, BH Park, TTP Tran, et al. Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signaling. Food Chem. 2013 ; 136(2):415-25.