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PGS. TS. Đồng Văn Quyền

Đồng Trưởng khoa

Quá trình học tập, công tác

1997: Cử nhân Sinh học, chuyên ngành Vi sinh vật học. Trường Đại học KHTN, ĐHQG Hà Nội

2002: Thạc sĩ Sinh học. Viện Sinh thái và Tài nguyên sinh vật, Viện Hàn lâm KHCN Việt Nam.

2006: Tiến sĩ Y sinh. Đại học Y Sungkyunkwan, Hàn Quốc.

Hướng nghiên cứu

Nghiên cứu phát triển kit chẩn đoán các tác nhân gây bệnh trên người và động vật như virus, vi khuẩn

Dịch tễ học phân tử của các tác nhân gây bệnh

Nghiên cứu phát triển các vaccine tái tổ hợp, vaccine thế hệ mới

Hệ gen, đặc tính di truyền và nghiên cứu định hướng ứng dụng.

Các công trình công bố

    1. Bo-Ram Yun , A-Tai Truong, Yong Soo Choi, Man Young Lee, Byoung Yong Kim, Minjung Seo, Soon-Seek Yoon, Mi-Sun Yoo, Dong Van Quyen*, Yun Sang Cho*. Comparison of the gut microbiome of sacbrood virus-resistant and -susceptible Apis cerana from South Korea. Sci Rep12(1):doi: 10.1038/s41598-022-13535-0 (2022
    2. Le Thu N., Le Thi Minh T., Pham Bich N., Trinh Thi Thu H., Dong Van Quyen., Ngo Dinh B., Chu Hoang H., Hoang H., Nguyen Van D. Detection of a novel Cry2Ab toxin against Etiella zinckenella Treitschke from the Bacillus thuringiensis serovar canadensis SP142 strain. Plant Protection Science, 58(2): 158–169 (2022)
    3. Pham Thi Lanh, Huong Minh Nguye, Bui Thi Thuy Duong, Nguyen Thi Hoa, Le Thi Thom, Luu Thi Tam, Ha Thi Thu, Vo Van Nha, Dang Diem Hong, Aidyn Mouradov, Apurav Krishna Koyande, Pau-Loke Show, Dong Van Quyen. Generation of microalga Chlamydomonas reinhardtii expressing VP28 protein as oral vaccine candidate for shrimps against White Spot Syndrome Virus (WSSV) infection. Aquaculture 540 (2021) 736737 (2021).
    4. Le Thi Nhi Cong, Do Thi Lien, Cung Thi Ngoc Mai, Nguyen Viet Linh, Nguyen Quang Lich, Hoang Phuong Ha, Dong Van Quyen, Tang DYY, Show PL. Advanced materials for immobilization of purple phototrophic bacteria in bioremediation of oil-polluted wastewater. Chemosphere 278:130464 (2021) 
    5. Tran Xuan Thach, Nguyen Thi Kim Lien, Ha Thi Thu, Nguyen Dinh Duy, Bui Thi Thuy Duong and Dong Van Quyen. Changes in the spike and nucleocapsid protein of porcine epidemic diarrhea virus strain in Vietnam—a molecular potential for the vaccine development ?. PeerJ 9: e12329 (2021)
    6. Khanh Minh Chau, Thi Thu Hao Van, Dong Van Quyen, Hung Dinh Le, Trinh Hoai Thi Phan, Ngoc Duy Thi Ngo, Trang Dieu Thi Vo, Trung Thanh Dinh, Hoa Thi Le and Huynh Hoang Nhu Khanh. Molecular Identification and Characterization of Probiotic Bacillus Species with the Ability to Control Vibrio spp. in Wild Fish Intestines and Sponges from the Vietnam Sea. Microorganisms 9: 1927 (2021)
    7. Le Thi Van Anh, Nguyen Ngoc Lien, Nguyen Quang Huy, Dong Van Quyen, Do Thi Yen, and Nguyen Thi Kieu Oanh. Phytochemical Screening and Potential Antibacterial Activity of Defatted and Nondefatted Methanolic Extracts of Xao Tam Phan (Paramignya trimera (Oliv.) Guillaum) Peels against Multidrug-Resistant Bacteria. Scientifica 4233615 (2021)
    8. Ha T Thu, Nguyen T K Lien, Pham T Lanh, Bui T T Duong, Nguyen T Hoa, Man H Phuoc, Pham H Thai and Dong Van Quyen. Genome analysis and phylogenetic characterization of two deformed wing virus strains from Apis cerana in Vietnam. PeerJ 8: e9911 (2020)
    9. Trang Thu Le, Thach Xuan Tran, Long Phi Trieu, Christopher M Austin, Huong Minh Nguyen and Dong Van Quyen. Genotypic characterization and genome comparison reveal insights into potential vaccine coverage and genealogy of
      Neisseria meningitidis in military camps in Vietnam. PeerJ 8: e9502 (2020).
    10. Bui Thi Thuy Duong, Nguyen Thi Kim Lien, Ha Thi Thu, Nguyen Thi Hoa, Pham Thi Lanh, Bo Ram Yn, Mi Sun Yoo, Yun Sang Cho, Đồng Văn Quyền. Investigation of the gut microbiome of Apis cerana honeybees from Vietnam. Biotechnol Lett 42: 2309-2317 (2020).
    11. Khanh Minh Chau, Dong Van Quyen, Joshua M Fraser, Andrew T Smith, Thu Thu Hao Van and Robert J Moore. Broad spectrum antimicrobial activities from spore-forming bacteria isolated from the Vietnam Sea. PeerJ 8:e10117 (2020).
    12. Nhung Thi Trang Trinh, Hieu Quang Tran, Dong Van Quyen, Christian Camnillau, Alain Roussel and Philippe Leone. crystal structure of type iX secretion system pore c-terminal domain from Porphyromonas gingivalis in complex with a
      peptidoglycan fragment. Scientific Reports 10:7384 (2020).
    13. Dong Van Quyen, Han Min Gan, Yin Peng Lee, Dinh Duy Nguyen, Thi Hoa Nguyen, Xuan Thach Tran, Van Sang Nguyen, Dinh Duy Khang, Christopher M. Austin. Improved genomic resources for the black tiger prawn (Penaeus monodon). Marine Genomics 52 (2020).
    14. Phuong T.M. Nguyen, Minh T.H. Nguyen, Lien T. Quach, Phuong T.M. Nguyen, Lam L. Nguyen, Dong V. Quyen. Antibiofilm activity of alpha-mangostin loaded nanoparticles against Streptococcus mutans. Asian Pacific Journal of Tropical Biomedicine 10(7): 325-332 (2020)
    15. Thanh Thi Minh Le, Anh Thị Hong Hoang, Nhue Phuong Nguyen, Thuy Thi Bich Le, Ha Thi Thu Trinh, Thuy Thu Bich Vo, Dong Van Quyen. A novel huperzin A-producing endophytic fungus Fusarium sp. Rsp5.2 isolated from Huperzia serrate. Biotechnology Letters 42: 987-995 (2020).
    16. Le Thi Nhi Cong, Do Thi Lien, Bhaskar Sen Gupta, Cung Thi Ngoc Mai, Hoang Phuong Ha, Nguyen Thi Minh Nguyet, Tran Hoa Duan, Dong Van Quyen, Hayyiratul Fatimal Mohd Zaid, Revathy Sankaran, Pau Loke Show. Enhances degradation of Diesel oil by using biofilms formed by indigenous purple photosynthetic bacteria from Oil-contaminated coasts of Vietnam of different carriers. Anplied Biochemistry and Biotechnology 191: 313-330 (2020).
    17. Nguyen NT, Bui NX, Nguyen VL, Nguyen VK, Kikuchi K, Nguyen HT, Nguyen HT, Nguyen HT, Dong Van Quyen, Chu HH, Cuc NTK, Somfai T. Optimization of in vitro embryo production and zygote vitrification for the indigenous Vietnamese Ban pig: The effects of different in vitro oocyte maturation systems. Anim Sci J. 2020 Jan-Dec;91(1):e13412. doi: 10.1111/asj.13412.
    18. Thanh Thi Minh Le, Anh Thi Hong Hoang, Thuy Thi Bich Le, Thuy Thi Bich Vo, Dong Van Quyen, Ha Hoang Chu. Isolation of endophytic fungi and screening of Huperzine A-producing fungus from Huperzia serrata in Vietnam. Scientific reports 9 (2019).
    19. Thach Xuan Tran, Trang Thu Le, Long Phi Trieu, Christopher M. Austin, Dong Van Quyen, Huong Minh Nguyen. Whole-genome sequencing and characterization of an antibiotic resistant Neisseria meningitides B isolate from a military unit in Vietnam. Annals of Clinical Microbiology and Antimicrobials 18(1): 16 (2019).
    20. Revathy Sankaran, Pau Loke Show, Yu Shen Cheng, Yang Tao, Xia Ao, Thi Dong Phuong Nguyen, Dong Van Quyen. Integration process for protein extraction from microalgae using liquid biphasic electric flotation (LBEF) system. Molecular Biotechnology 60: 749-761 (2018).
    21. Nguyen Viet Linh, Tamas Somfai, Thi Hiep Nguyen, Nguyen Thi Nhung, Nguyen Thi Hong, Nguyen Tien Dat, Nguyen Hoang Trinh, Nguyen Khanh Van, Dong Van Quyen, Hoang Ha Chu, Nguyen Thanh Son, Kazuhiro Kikuchi. Optimization of the in vitro fertilization protocol for frozen epididymal sperm with low fertilization ability in Ban—A native Vietnamese pigs. Animal Science Journal 89(8): 1079-1084 (2018).
    22. Nguyen Huy Thuan, Nguyen Thanh Trung, Nguyen Xuan Cuong, Duong Van Cuong, Dong Van Quyen, Sailesh Malla. Escherichia coli modular coculture system for resveratrol glucosides production. World Journal of Microbiology and Biotechnology 34(6):75 (2018).
    23. Kondreddy Eswar Reddy, Ha Thi Thu, Mi Sun Yoo, Mummadrieddy Ramya, Bheemireddy Anjana Reddy, Nguyen Thi Kim Lien, Nguyen Thi Phuong Trang, Bui Thi Thuy Duong, Hyun Jeong Lee, Seung Won Kang, Dong Van Quyen. Comparative Genomic Analysis for Genetic variation in Sacbrood virus of Apis cerana and Apis mellifera honeybees from different regions of Vietnam. Journal of Insect science 17(5): 101 (2017).
    24. Thi Tuyet Nhung Nguyen, Thi Thu Ha, Thi Hoa Nguyen, Thi Hien Vu, Nam Hai Truong, Hoang Ha Chu, Dong Van Quyen. Peptide Fraction pOh2 Exerts Antiadipogenic Activity through Inhibition of C/EBP-α and PPAR-γ Expression in 3T3-L1 Adipocytes. Biomed Research International (2017).
    25.  Ha Thi Thu, Nguyen Thi Kim Lien, Mai Thuy Linh, Thanh Hoa Le, Nguyen Thi Hoa, Pham Hong Thai, Kondreddy Eswar Reddy, Mi Sun Yoo, Young-Ha Kim, Yun Sang Cho, Seung Won Kang, Dong Van Quyen. Prevalence of bee viruses among Apis cerana populations in Vietnam. Journal of Apicultural Research (2016).
    26.  Cuong Nguyen, Thu Giang Nguyen, Lam Van Nguyen, Huy Quang Pham, Trieu Hai Nguyen, Hoa Thi Pham, Hoa Thi Nguyen, Thu Thi Ha, Tung Huy Dau, Hien Thi Vu, Duy Dinh Nguyen, Nhung Tuyet Thi Nguyen, Ninh Huu Nguyen, Dong Van Quyen, Ha Hoang Chu, Khang Duy Dinh. De novo assembly and transcriptome characterization of major growth-related genes in various tissues of Penaeus monodon. Aquaculture 464: 545–553 (2016).
    27.  Nguyen Hai Trieu, Nguyen Ngoc Huyen, Nguyen Huong Tra, Nguyen Thi Hong Ha, Harsharnjit S Gill, Nguyen Minh Huong, Dong Van Quyen. Enhancing the production of syringomycin E in Pseudomonas syringae pv syringae by random mutagenesis and molecular characterization of the SyrB1 gene. African Journal of Biotechnology (2016).
    28.  Le Thi Nhi Cong, Cung Thi Ngoc Mai, Nghiem Ngoc Minh, Hoang Phuong Ha, Do Thi Lien, Do Van Tuan, Dong Van Quyen, Michihiko Ike, Do Thi To Uyen. Degradation of sec-hexylbenzene and its metabolites by a biofilm-forming yeast Trichosporon asahii B1 isolated from oil-contaminated sediments in Quangninh coastal zone, Vietnam. Journal of Environmental Science and Heakth (2016).
    29.  Kondreddy Eswar Reddy, Jin HyeongNoh, Mi-SunYoo, Young-HaKim, Nam-Hee Kim, Huong Thi Thanh Doan, Mummadireddy Ramy, Suk-ChanJung, Dong Van Quyen, Seung-Won Kang. Molecular characterization and phylogenetic analysis of deformed wing viruses isolated from South Korea. Veterinary Microbiology (2013).
    30. Kang SW, Doan HT, Noh JH, Choe SE, Yoo MS, Kim YH, Reddy KE, Nguyen TT, Dong Van Quyen, Nguyen LT, Kweon CH, Jung SC. Seroprevalence of Toxoplasma gondii and Trichinella spiralis infections in wild boars (Sus scrofa) in Korea. Parasitol Int. 2013 62(6):583-5.
    31. Reddy KE, Noh JH, Kim YH, Yoo MS, Doan HT, Ramya M, Jung SC, Dong Van Quyen, Kang SW. Analysis of the nonstructural and structural polyprotein regions, and complete genome sequences of Israel acute paralysis viruses identified from honeybees (Apis mellifera) in Korea. Virology. 2013 444(1-2):211-7.
    32. Tung DH, Dong Van Quyen, Nguyen T, Xuan HT, Nam TN, Dinh Duy Khang. Molecular characterization of a H5N1 highly pathogenic avian influenza virus clade 2.3.2.1b circulating in Vietnam in 2011. Vet Microbiol. 2013 30;165(3-4):341-8
    33. Reddy KE, Noh JH, Yoo MS, Kim YH, Kim NH, Doan HT, Ramya M, Jung SC, Dong Van Quyen, Kang SW. Molecular characterization and phylogenetic analysis of deformed wing viruses isolated from South Korea. Vet Microbiol. 2013 Aug 30. doi:pii: S0378-1135(13)00417-3.
    34. Kang SW, Doan HT, Noh JH, Choe SE, Yoo MS, Kim YH, Reddy KE, Nguyen TT, Dong Van Quyen, Nguyen LT, Kweon CH, Jung SC. Seroprevalence of Toxoplasma gondii and Trichinella spiralis infections in wild boars (Sus scrofa) in Korea. Parasitol Int. 2013 doi:pii: S1383-5769(13)00130-X.
    35. Reddy KE, Noh JH, Kim YH, Yoo MS, Doan HT, Ramya M, Jung SC, Dong Van Quyen, Kang SW. Analysis of the nonstructural and structural polyprotein regions, and complete genome sequences of Israel acute paralysis viruses identified from honeybees (Apis mellifera) in Korea. Virology. 2013 44(1-2):211-7. 
    36. Doan HT, Noh JH, Choe SE, Yoo MS, Kim YH, Reddy KE, Dong Van Quyen, Nguyen LT, Nguyen TT, Kweon CH, Jung SC, Chang KY, Kang SW. Molecular detection and phylogenetic analysis of Anaplasma bovis from Haemaphysalis longicornis feeding on grazing cattle in Korea. Vet Parasitol. 2013;196(3-4):478-81. 
    37. Reddy KE, Noh JH, Choe SE, Kweon CH, Yoo MS, Doan HT, Ramya M, Yoon BS, Nguyen LT, Nguyen TT, Dong Van Quyen, Jung SC, Chang KY, Kang SW. Analysis of the complete genome sequence and capsid region of black queen cell viruses from infected honeybees (Apis mellifera) in Korea. Virus Genes. 2013;47(1):126-32.
    38. Noh JH, Reddy KE, Choe SE, Yoo MS, Doan HT, Kweon CH, Ramya M, Yoon BS, Nguyen LT, Nguyen TT, Dong Van Quyen, Jung SC, Chang KY, Kang SW. Phylogenetic analysis of black queen cell virus genotypes in South Korea. Virus Genes. 2013; 46(2):362-8.
    39. Le VP, Lee KN, Nguyen T, Kim SM, Cho IS, Dinh Duy Khang, Hien NB, Dong Van Quyen, Park JH. A rapid molecular strategy for early detection and characterization of Vietnamese foot-and-mouth disease virus serotypes O, A, and Asia 1. J Virol Methods. 2012;180(1-2):1-6.
    40. Kundumani-Sridharan V, Dong Van Quyen, Subramani J, Singh NK, Chin YE, Rao GN. Novel interactions between nuclear factor of activated T cells c1 and signal transducer and activator of transcription-3 modulate a biphasic expression of cyclin D1 with the first phase influencing cell migration and the second phase directing cell cycle progression. J Biol Chem. 2012 (doi/10.1074/jbc.M112.362996).
    41. Le VP, Lee KN, Nguyen T, Kim SM, Cho IS, Dong Van Quyen, Dinh Duy Khang, Park JH. Development of one-step multiplex RT-PCR method for simultaneous detection and differentiation of foot-and-mouth disease virus serotypes O, A, and Asia 1 circulating in Vietnam. J Virol Methods. 2011, 175(1):101-8.
    42. Singh NK, Wang D, Kundumani-Sridharan V, Dong Van Quyen, Niu J, Rao GN. 15-Lipoxygenase-1-enhanced Src-Janus Kinase 2-Signal Transducer and Activator of Transcription 3 Stimulation and Monocyte Chemoattractant Protein-1 Expression Require Redox-sensitive Activation of Epidermal Growth Factor Receptor in Vascular Wall Remodeling. J Biol Chem. 2011, 286(25):22478-88.
    43. Le TH, Le TB, Doan TTH, Dong Van Quyen, Le TKX, Pham VC, Nagataki M, Nomura H, Ikeue Y, Watanabe Y and Agatsuma T. The Adjuvant Effect of Sophy β-Glucan to the Antibody Response in Poultry Immunized by the Avian Influenza A H5N1 and H5N2 Vaccines. J. Microbiol Biotechnol. 2011, 21(4):405-11.  
    44. Singh NK, Dong Van Quyen, Kundumani-Sridharan V, Brooks Peter C and Rao GN. AP-1 (Fra-1/c-jun-mediated induction of expression of matrix metalloproteinase-2 is required for 15(S)-Hydroxyeicosatetraenoic acid-induced angiogenesis. J Biol Chem. 2010, 285(22):16830-43. 
    45. Karpurapu M, Wang D, Dong Van Quyen, Kim TK, Kundumani-Sridharan V, Pulusani S, Rao GN. Cyclin D1 is a bona fide target gene of NFATc1 and is sufficient in the mediation of injury-induced vascular wall remodeling. J Biol Chem. 2010, 285:3510-23.
    46. Kundumani-Sridharan V, Niu J, Wang D, Dong Van Quyen, Zhang Q, Singh NK, Subramani J, Karri S, Rao GN. 15(S)-hydroxyeicosatetraenoic acid-induced angiogenesis requires Src-mediated Egr-1-dependent rapid induction of FGF-2 expression. Blood. 2010, 115:2105-16.
    47. Potula HS, Wang D, Dong Van Quyen, Singh NK, Kundumani-Sridharan V, Karpurapu M, Park EA, Glasgow WC, Rao GN. Src-dependent STAT-3-mediated expression of monocyte chemoattractant protein-1 is required for 15(S)-hydroxyeicosatetraenoic acid-induced vascular smooth muscle cell migration. J Biol Chem. 2009. 284:31142-55.
    48. Seung-Won Kang, Park Eun-Hang Lee, Young-Hwa Jean, Se-Eun Choe, Dong Van Quyen. Characterization of tissue distribution and histopathological lesions in Neospora caninum experimentally infected gerbils. Parasitol Res. 2009, 104:1261-8.
    49.  Seung-Won Kang, Eun-Hang Lee, Young-Hwa Jean, Se-Eun Choe, Dong Van Quyen*, and Myeong-Sok Lee. The differential protein expression profiles and immunogenicity of tachyzoites and bradyzoites of in vitro cultured Neospora caninum. Parasitol Res. 2008,103:905-13. 
    50. Seung-Won Kang, Chang-Hee Kweon, Eun-Hang Lee, Se-Eun Choe, Suk-Chan Jung, Dong Van Quyen. The differentiation of transcription between tachyzoites and bradyzoites of in vitro cultured Neospora caninum. Parasitol Res. 2008, 103:1011-8. 
    51. Dong Van Quyen, Sung Chul Ha, Ky Lowenhaupt, Alexander Rich, Kyeong Kyu Kim and Yang-Gyun Kim. Characterization of DNA-binding activity of Z alpha domains from poxviruses and the importance of the beta-wing regions in converting B-DNA to Z-DNA. Nucleic Acids Res. 2007, 35:7714-20.
    52. Dong Van Quyen, Sung Chul Ha, Doyoun Kim, Sangho Lee, So-Jung Park, Kyeong Kyu Kim,Yang-Gyun Kim. Binding surface in Zβ domain from human ZBP1 does not rquire conserved praline residue for Z-DNA bidning and B-toZ-DNA conversion activities. Bull. Korean Chem.Soc. 2007, 28: 2539-42.
    53. Dong Van Quyen, Yang-Gyun Kim, Kyeong Kyu Kim. Sequence-dependent kinetic behavior of protein-induced B- to Z-DNA transition. Bull Korean. Chem. So., 2006, 27:1071-74.
    54. Sung Chul Ha, Dong Van Quyen, Hye-Yeon Hwang, Doo-Byoung Oh, Bernard A. Brown II, Seon Min Lee, Hyun-Ju Park, Jin-Hyun Ahn, Kyeong Kyu Kim and Yang-Gyun Kim. Biochemical characterization and preliminary X-ray crystallographic study of the domains of human ZBP1 bound to left-handed Z-DNA. Biochimica et Biophysica Acta (BBA) – Proteins & Proteomics, 2006, 1764:320-3.
    55. Sung Chul Ha, Neratur K. Lokanath, Dong Van Quyen, Chun Ai Wu, Ky Lowenhaupt, Alexander Rich, Yang-Gyun Kim, and Kyeong Kyu Kim. A poxvirus protein forms a complex with left-handed Z-DNA: crystal structure of a Yatapoxvirus Zα bound to DNA. Proc Natl Acad Sci U S A. 2004, 101:14367-72.
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