• Description
In this project, the design of organic  materials  (conducting,  semi-conducting)  and  metallic  nanoparticles  will  be emphasized  with  development  in  environmental  and  biomedical  applications.  The first applications to be developed concern environmental and biomedical sensors.
Despite  some  recent  advances,  the  detection  of  traces  of  (bio-)chemical  contaminants  in  food  or environment (water, soils …) as well as biomarkers specific of some diseases in medical diagnosis remains a challenge, in France or in Vietnam. For example, one of the most rapidly advancing fields in medical diagnosis is point of care (POC) testing.  The  aim  is  the  development  of  potentially  portable  set-up  that allows  a whole diagnostic panel directly on-site (in the doctor's office or the emergency ward, for example) where regular  assays  cannot  be  performed  since  they  are  time-consuming.  For other applications, the rapid detection of contaminants is important to estimate any damage on the environment, or for food quality control. Analysis are currently achieved through very classical tools such as chromatographic techniques coupled to mass spectrometry.  
Due  to  their  complexity,  the  design  of  highly  sensitive  and  specific  sensing  devices  requires  an interdisciplinary collaboration (chemistry, physics, and biology) and complementary expertise between research groups that cannot be found at a single laboratory level. Via an international research project, one can  take  profit  of  the  most  recent  advances  in  nanomaterials,  micro- and  bio-technologies  to develop innovative biosensors devoted to the detection of contaminants and biomarkers, able to detect traces with high sensitivity expected around the sub-femtomolar (10-15M) range.
With the view of potential applications in environment, biology and medicine, the development of such sensors at the nanoscale must gain much attention in this program. Due to confinement and plasmon effect interesting novel properties can be anticipated at the nano-structuration scale.  Elaborated  coordination  complexes  are  versatile;  one,  two  or  three different ligands can be organized around the metal in order to insure (i) a robust interaction with a surface (they  can be  covalently  bonded  to  a  silica,  or  metallic  surface),  (ii)  physical  property,  and  (iii)  free position for potential reactivity with a gaz.
  • Team 
PI : PHAM Minh Chau, Paris Diderot                                                  
Co-PI : TRAN Dai Lam, IMS-VAST                                                      
NGUYEN Tuan Dung, ITT-VAST                                                   
UNG Thi Dieu Thuy, IMS-VAST                                          
VU Hoang Chung, IMS-VAST                                                  
NGUYEN Quang Liem, IMS-VAST                                              
VU Thi Thu, USTH                                       
Benoit PIRO, Paris Diderot                                           
Jean-Christophe LACROIX, Paris Diderot                                                 
Marion WOYTASIK, Paris Sud                                                
Philippe LECOEUR, Paris Sud                                                 
Fayna MAMMERI, Paris Diderot                                           
Steeve REISBERG, Paris Diderot                                        
Nordin FELIDJ, Paris Diderot                                                 
Delphine SCHAMING, Paris Diderot                                              
Pascal MARTIN (Paris Diderot)                                                   
Jalal GHILANE, Paris Diderot                                                    
Catherine AMIENS, Université Paul sabatier                                                    
Diana CIUCULESCU, Université Paul Sabatier                                               
Karine PHILIPPOT, Laboratoire de Chimie de coordination CNRS                                                     
Pierre LECANTE, Centre d'Elaboration et d'Etudes Structurales CNRS                                              
Gilles LEMERCIER, Université de Reims                                         
Philippe DANIEL, Université du Maine                                             
  • PhD students                                                                                 
TRAN Ving Hoang, USTH Phd Student