Dr. Tran Thi Thu Phuong

Qualifications 

• 2010: Pharmacist, Hanoi University of Pharmacy
• 2013: Master of Science in Pharmaceutical Science, Hanoi National University of Education
• 2017: PhD degree in Health Biology –Montpellier Institute for Molecular Genomics, Center National Research in Science, Lab adenovirus: receptors, transporters and vectors. University of Monpellier 2

Research interests

• Evaluate biological activities and research on molecular mechanisms related to immune response, cancer and anti-inflammatory of substances/extracts derived from medicinal herbs and other drugs/ dosage forms

Selected publications

1. Tran Thi Thu Phuong1, Nguyen Hai Dang1,*, Nguyen Thi Hong Anh2, Do Hoang Giang2, Nguyen Tien Dat2,*. A new megastigmane glycoside and other constituents from Amomum muricarpum Elmer. Records of Natural Products-http://doi.org/10.25135/rnp.333.2203.2395
2. Tuan Hiep Tran#, TTPTran. Targeting the PD-1/PD-L1 axis for cancer treatment: a review on nanotechnology.  Royal Society Open Science. 2022 Apr 13;9(4):211991. doi: 10.1098/rsos.211991.
3. Minh Quang Pham, Duong Thi Bach Nguyen, TTP Tran. Pain relief after maxillofacical surgery : efficacy in patients undergoing ultrasound-guided trigeminal nerve block-a randomized controlled trial. Biomedical Research and Therapy. Vol 9 No 1 (2022) / 4865-4872
4. Karsten Eichholz, Tuan Hiep Tran, Coraline Chéneau, TTP Tran, Océane Paris, Martine Pugniere, and Eric Kremer. Adenovirus-α-defensin complexes induce NLRP3-associated maturation of human phagocytes via TLR4 engagement. Journal of virology. 2022 Jan 26 https://doi.org/10.1128/jvi.01850-21
5. TTP Tran#, Tuan Hiep Tran and Eric J Kremer. IgG-complexed adenovirus induce human plasmacytoid dendritic cell activation and apoptosis. Virus. 27 Aug 2021 13(9):1699. doi: 10.3390/v13091699.
6. Coraline Chéneau #, Karsten Eichholz#, Tuan Hiep Tran #, TTPT Tran  et al. Lactoferrin retargets human adenovirus to TLR4 to Induce an abortive NLRP3-asociated pyroptotic response in human phagocytes. Front. Immunol., 20 May 2021
7. TH Tran#, TTP Tran#, DH Truong et al. Toll-like receptor-targeted particles: A paradigm to manipulate the tumor microenvironment for cancer immunotherapy. Acta Biomater 2019 Aug, 94:82-96.
8. Dai Cao Phung, Hanh Thuy Nguyen, TTP Tran et al. Combined hyperhermia and chemotherapy as a synergistic anticancer treatment. Journal of pharmaceutical investigation. 6 March 2019
9. TTP Tran#, K Eichholz, P Amelio, et al. Humoral immune response to adenovirus induce tolerogenic dendritic cells that promote generation of regulatory T cells. Plos pathogens 2018 Aug 20;14(8)
10. HT Truong#, TTP Tran, HT Nguyen, et al. Modulating T-cell-based cancer immunotherapy via particulate systems. J Drug Targeting 2018 Jun 3:1-19. 
11. TH Tran#, TTP Tran, HT Nguyen, et al. Nanoparticles for dendritic cell-based immunotherapy. International journal of pharmaceutics 2018; 542(1-2):253-265.
12. TH Tran#, Hanh Thuy Nguyen, Nam Van Le, TTP Tran et al. Engineering of multifunctional temperature-sénitive liposomes for synergistic photothermal, photodynamic, and chemotherapeutic effects. International journal of pharmaceutics, Vol 528, issue 1-2, page 692-704, 7 August 2017. 
13. FJ Mennechet#, K Eichholz,  TTP Tran, Eric J. Immunité humorale anti-adénovirus Impact sur l’activation des cellules dendritiques Anti-adenovirus humoral immunity: impact on dendritic cell activation. Med Sci (Paris), Vol 33, No 6-7, Page 582-585 July 2017.
14. TH Tran#, Hanh Thuy Nguyen, TTP Tran et al.  Combined photothermal and photodynamic thẻapy by hyaluronic acid-decorated polyrrole nanoparticles. Nanomedicine, Vol 12, No 12, 2 Jun 2017.
15. K Eichholz#, T Bru, TTP Tran, et al. Immune-complexed adenoviruses induce AIM2-mediated pyroptosis in human dendritic cells. Plos pathogen 2016;12(9).
16. FJ Mennechet#, TTP Tran, K Eichholz et al. Ebola virus vaccine: benefit and risks of adenovirus-based vectors. Expert review of vaccines, 2015. 14(11):1471-8.
17. MT Do#, HG Kim, TTP Tran, et al. Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression. Toxicology and Applied Pharmacology, 2014;280(1):138-48. 
18. MT Do#, HG Kim, JH Choi, T Khanal, BH Park, TTP Tran, et al. Antitumor efficacy of piperine in the treatment of human HER2-overexpression brest cancer cells. Food Chem. 2013; 141(3):2591-9. 
19. TTP Tran#, HG Kim, MK Na, HG Jeong. Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. Phytomedicine 2013;20(7):622-31.
20. HY Pil#, HG Kim, Choi JH, MT Do, TTP Tran, et al. 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea attenuates high glucose-induced hepatic lipogenesis in human HepG2 cells through activation of the liver kinase B1 and silent information regulator T1/AMPK-dependent pathway.Mol Nutr Food Res. ;57(3):471-82. 
21. HG Kim#, EH Han, WS Jang, JH Choi, T Khanal, BH Park, TTP Tran, et al. Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages. Food Chem Toxicol. 2012 ;50(7):2342-8. 
22. MT Do#, HG Kim, JH Choi, T Khanal, BH Park, TTP Tran, et al. Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signaling. Food Chem. 2013 ; 136(2):415-25.