Dr. Tran Thi Thu Phuong

Qualifications 

• 2010: Pharmacist, Hanoi University of Pharmacy
• 2013: Master of Science in Pharmaceutical Science, Hanoi National University of Education
• 2017: PhD degree in Health Biology –Montpellier Institute for Molecular Genomics, Center National Research in Science, Lab adenovirus: receptors, transporters and vectors. University of Monpellier 2

Research interests

• Evaluate biological activities and research on molecular mechanisms related to immune response, cancer and anti-inflammatory of substances/extracts derived from medicinal herbs and other drugs/ dosage forms

Selected publications

1. Duy Hieu Truong, TTPTran, Tuan Hiep Tran. Nanoparticles as carriers of photosensitizers to improve photodynamic therapy in cancer. 2024. ISSN: 1097-9867
2. Uyen Thi Tu Phan, Hai Dang Nguyen, Thi Kieu Oanh Nguyen, Tuan Hiep Tran, Thanh Huong Le, TTPTran. Anti-inflammatory effect of Piper longum L. fruit methanolic extract on lipopolysaccharide-treated RAW 264.7 murine macrophages. 2024. Vol 10, Issue 4, E26174. ISSN: 2405-8440
3. Chien Ngoc Nguyen, Bien Trong Tran, Bao Ngoc Tran, Gam Thi Trinh, Hien Thi Pham, Uyen Tu Phan, TTPTran, Sy Viet Nguyen. Formulation of nanoparticulate andrographolide-incorporated gel for dermal delivery. 2022. BioNanoScience. 13(4):1-11. ISSN: 21911630; 21911649
4. Thu Kim Dang, Seong-Min Hong, Vui Thi Dao, TTPTran, Hiep Tuan Tran, Giang Hoang Do, Thanh Nguyen Hai, Hang Thi Nguyet Pham and Sun Yeou Kim. Anti-neuroinflammatory effects of alkaloid-enriched extract fromHuperzia serrataon lipopolysaccharide-stimulated BV-2 microglial cells. 2023. Pharmaceutical biology. Vol. 61, No. 1, 135–143. ISSN: 1388-0209 (print); 1744-5116 (web)
5. Minh Quang Pham, Anh Xuan Nguyen, TTPTran. Bilateral superficial cervical plexus block improves pain control after thyroidectomy under general anesthesia: a randomized, double-blind, clinical trial. 2023. Anaesthesia, Pain and Intensive Care. Vol (27 (2).ISSN: 1607-8322.
6. Hiep Tran, TTPTran, Hieu Duy Truong. Lactoferrin and nanotechnology: The potential for cancer treatment.  2023. Pharmaceutics. 15(5), 1362. ISSN: 18733476, 03785173
7. TTPTran, Nguyen Hai Dang^1,*, Nguyen Thi Hong Anh², Do Hoang Giang², Nguyen Tien Dat^2,*. A new megastigmane glycoside and other constituents from Amomum muricarpum Elmer. Records of Natural Products-http://doi.org/10.25135/rnp.333.2203.2395
8. Tuan Hiep Tran#, TTPTran. Targeting the PD-1/PD-L1 axis for cancer treatment: a review on nanotechnology.  RoyalSociety Open Science. 2022 Apr 13;9(4):211991. doi: 10.1098/rsos.211991.
9. Minh Quang Pham, Duong Thi Bach Nguyen, TTP Tran. Pain relief after maxillofacical surgery : efficacy in patients undergoing ultrasound-guided trigeminal nerve block-a randomized controlled trial. Biomedical Research and Therapy. Vol 9 No 1 (2022)/ 4865-4872
10. Karsten Eichholz, Tuan Hiep Tran, Coraline Chéneau, TTP Tran, Océane Paris, Martine Pugniere, and Eric Kremer. Adenovirus-α-defensin complexes induce NLRP3-associated maturation of human phagocytes via TLR4 engagement. Journal of virology. 2022 Jan 26 https://doi.org/10.1128/jvi.01850-21 
11. TTP Tran, Tuan Hiep Tran and Eric J Kremer. IgG-complexed adenovirus induce human plasmacytoid dendritic cell activation and apoptosis. Virus. 27 Aug 2021 13(9):1699. doi: 10.3390/v13091699.
12. Coraline Chéneau , Karsten Eichholz, Tuan Hiep Tran, TTPT Tran et al. Lactoferrin retargets human adenovirus to TLR4 to Induce an abortive NLRP3-asociated pyroptotic response in human phagocytes. Front. Immunol., 20 May 2021.
13. TH Tran, TTP Tran, DH Truong et al. Toll-like receptor-targeted particles: A paradigm to manipulate the tumor microenvironment for cancer immunotherapy. Acta Biomater 2019 Aug, 94:82-96.
14. Dai Cao Phung, Hanh Thuy Nguyen, TTP Tran et al. Combined hyperhermia and chemotherapy as a synergistic anticancer treatment. Journal of pharmaceutical investigation. 6 March 2019.
15. TTP Tran, K Eichholz, P Amelio, et al. Humoral immune response to adenovirus induce tolerogenic dendritic cells that promote generation of regulatory T cells. Plos pathogens 2018 Aug 20;14(8)
16. HT Truong, TTP Tran, HT Nguyen, et al. Modulating T-cell-based cancer immunotherapy via particulate systems. J Drug Targeting 2018 Jun 3:1-19.
17. TH Tran, TTP Tran, HT Nguyen, et al. Nanoparticles for dendritic cell-based immunotherapy. International journal of pharmaceutics 2018; 542(1-2):253-265.
18. TH Tran, Hanh Thuy Nguyen, Nam Van Le, TTP Tran et al. Engineering of multifunctional temperature-sénitive liposomes for synergistic photothermal, photodynamic, and chemotherapeutic effects. International journal of pharmaceutics, Vol 528, issue 1-2, page 692-704, 7 August 2017.
19. FJ Mennechet, K Eichholz, TTP Tran, Eric J. Immunité humorale anti-adénovirus Impact sur l’activation des cellules dendritiques Anti-adenovirus humoral immunity: impact on dendritic cell activation. Med Sci (Paris), Vol 33, No 6-7, Page 582-585 July 2017.
20. TH Tran, Hanh Thuy Nguyen, TTP Tran et al. Combined photothermal and photodynamic thẻapy by hyaluronic acid-decorated polyrrole nanoparticles. Nanomedicine, Vol 12, No 12, 2 Jun 2017.
21. K Eichholz, T Bru, TTP Tran, et al. Immune-complexed adenoviruses induce AIM2-mediated pyroptosis in human dendritic cells. Plos pathogen 2016;12(9).
22. FJ Mennechet, TTP Tran, K Eichholz et al. Ebola virus vaccine: benefit and risks of adenovirus-based vectors. Expert review of vaccines, 2015. 14(11):1471-8.
23. MT Do, HG Kim, TTP Tran, et al. Metformin suppresses CYP1A1 and CYP1B1 expression in breast cancer cells by down-regulating aryl hydrocarbon receptor expression. Toxicology and Applied Pharmacology, 2014;280(1):138-48.
24. MT Do#, HG Kim, JH Choi, T Khanal, BH Park, TTP Tran, et al. Antitumor efficacy of piperine in the treatment of human HER2-overexpression brest cancer cells. Food Chem. 2013; 141(3):2591-9.
25. TTP Tran, HG Kim, MK Na, HG Jeong. Reversal of P-glycoprotein-mediated multidrug resistance is induced by mollugin in MCF-7/adriamycin cells. Phytomedicine 2013;20(7):622-31.
26. HY Pil, HG Kim, Choi JH, MT Do, TTP Tran, et al. 3-Caffeoyl, 4-dihydrocaffeoylquinic acid from Salicornia herbacea attenuates high glucose-induced hepatic lipogenesis in human HepG2 cells through activation of the liver kinase B1 and silent information regulator T1/AMPK-dependent pathway.Mol Nutr Food Res. ;57(3):471-82.
27. HG Kim, EH Han, WS Jang, JH Choi, T Khanal, BH Park, TTP Tran, et al. Piperine inhibits PMA-induced cyclooxygenase-2 expression through downregulating NF-κB, C/EBP and AP-1 signaling pathways in murine macrophages. Food Chem Toxicol. 2012 ;50(7):2342-8.
28. MT Do, HG Kim, JH Choi, T Khanal, BH Park, TTP Tran, et al. Phillyrin attenuates high glucose-induced lipid accumulation in human HepG2 hepatocytes through the activation of LKB1/AMP-activated protein kinase-dependent signaling. Food Chem. 2013 ; 136(2):415-25.