Research interests
- Nanomedicine and targeted drug delivery: Design of functional nanoparticles to improve therapeutic efficacy and reduce toxicity.
- Cancer therapy and immunomodulation: Development of nanoparticle platforms combining chemotherapy and immunotherapy to enhance antitumor immune responses.
- Natural bioactive compounds and pharmaceutical analysis: Investigation of plant-derived bioactives supported by in vitro/in silico studies and development of analytical methods for drug quality control.
Selected publications
- Thi-Van-Anh Nguyen, Le Minh Pham, Nguyen T. Minh Huyen, Hai Pham-The et al. 2026, Beyond α-Glucosidase and α-Amylase Inhibition: Integrated In Vitro and Multi-Scale In Silico Insights into the Antidiabetic and Antioxidant Mechanisms of Oxalis corniculata L. Aerial Parts, Molecules (ISSN: 1420-3049) https://doi.org/10.3390/molecules31040630
- Ye Gu , Bao Loc Nguyen , Mahesh Pandit, Le Minh Pham, et al. 2025 Nanoparticle-based methionine and AICAR delivery elicits a robust antitumor immune response, Journal of Controlled Release (ISSN: 1873-4995), https://doi.org/10.1016/j.jconrel.2025.113981
- Tiep Tien Nguyen, Mai Thi Phuong, Manju Shrestha, Junhyeung Park, Le Minh Pham, et al. 2023 Scalable and Uniform Fabrication of Dexamethasone-Eluting Depot-Engineered Stem Cell Spheroids as a Microtissue Construct to Target Bone Regeneration, ACS Applied Materials & Interfaces (ISSN: 1944-8244), https://doi.org/10.1021/acsami.3c03102
- Hanh Thuy Nguyen, Cao Dai Phung, Tuan Hiep Tran, Tung Thanh Pham, Le Minh Pham, et al. 2021 Manipulating immune system using nanoparticles for an effective cancer treatment: Combination of targeted therapy and checkpoint blockage miRNA, Journal of Controlled Release (ISSN: 1873-4995), https://doi.org/10.1016/j.jconrel.2020.09.034
- Kishwor Poudel, Asmita Banstola, Milan Gautam, Zar Chi Soe, Le Minh Pham, et al. 2021 Redox/photo dual-responsive, self-targeted, and photosensitizer-laden bismuth sulfide nanourchins for combination therapy in cancer Nanoscale (ISSN: 2040-3372),
https://doi.org/10.1039/D0NR07736D - Le Minh Pham, Eok-Cheon Kim, Wenquan Ou, Cao Dai Phung, et al. 2021 Targeting and clearance of senescent foamy macrophages and senescent endothelial cells by antibody-functionalized mesoporous silica nanoparticles for alleviating aorta atherosclerosis, Biomaterials (ISSN: 0142-9612),
https://doi.org/10.1016/j.biomaterials.2021.120677 - Le Minh Pham, Kishwor Poudel, Wenquan Ou, Cao Dai Phung, et al. 2021 Combination chemotherapeutic and immune-therapeutic anticancer approach via anti-PD-L1 antibody conjugated albumin nanoparticles, International Journal of Pharmaceutics (ISSN: 0378-5173),
https://doi.org/10.1016/j.ijpharm.2021.120816 - Le Minh Pham, Kishwor Poudel, Cao Dai Phung, Tien Tiep Nguyen, et al. 2021 Preparation and evaluation of dabrafenib-loaded, CD47-conjugated human serum albumin-based nanoconstructs for chemoimmunomodulation, Colloids and Surfaces B: Biointerfaces (ISSN: 0927-7765),
https://doi.org/10.1016/j.colsurfb.2021.112093
For further information:
| ORCID ID | https://orcid.org/0000-0002-6013-1956 |
| Google Scholar | https://scholar.google.com/citations?user=-006FOsAAAAJ&hl=vi |
| Research Gate | https://www.researchgate.net/profile/Pham-Le-Minh?ev=hdr_xprf |
