Qualifications
- 2009: Bachelor of Chemical Technology. College of Science, Vietnam national University, Hanoi
- 2011: Master of Chemistry – Durable technology. University of Technologies of Compiegne, France
- 2015: Doctor of Chemistry – Biology – Health. University of Toulouse III, France
Research interests
- Analytical chemistry: LC-MS, GC-MS, UV-Vis, IR
- Chemistry of natural compounds: Extraction and isolation of pure compounds, quantification of bioactive compounds targeting for drug development
- Bioactivities: Anti-platelet aggregation and anticoagulant activity, anti-diabetic and antioxidant effects.
Selected publications
- Hong Luyen Le, Thi Minh Hang Nguyen, Thi Thom Vu, Thi Tu Oanh Nguyen, Huong Duong Thi Ly, Nguyen Thanh Le, Van Hung Nguyen, Thi Van Anh Nguyen. Potent antiplatelet aggregation, anticoagulant and antioxidant activity of aerial Canna x generalis L.H Bailey & E.Z Bailey and its phytoconstituents. South African Journal of Botany, 2022, 147, 882 – 893.
- Le Hong Luyen, Vu Thi Thom, Le Thi Thanh Huong, Duong Thi Ly Huong, Nguyen Thi Van Anh. Inhibitory Effect on Human Platelet Aggregation, Antioxidant Activity, and Phytochemicals of Canna warszewiczii (A. Dietr) Nb. Tanaka. Pharmacognosy Research, 2020, 12, 47-52.
- Thi Minh Hang Nguyen, Hong Luyen Le, Thi Thoa Ha, Bich Hau Bui, Nguyen Thanh Le, Van Hung Nguyen, Thi Van Anh Nguyen. Inhibitory effect on human platelet aggregation and coagulation and antioxidant activity of C. edulis Ker Gawl rhizome and its secondary metabolites. Journal of Ethnopharmacology, 2020, 263, 113-136 .
- Hong-Luyen Le, Dao-Cuong To, Manh-Hung Tran, Thi-Thuy Do, and Phi-Hung Nguyen. Natural PTP1B inhibitors from Polygonum cuspidatum and their 2-NBDG uptake stimulation. Natural Product Communications, 2020, 15(9), 1–7.
- Le Hong Luyen, Pham Minh Quan, Nguyen Phi Hung. Protein tyrosine phosphatase 1B inhibitory activities of compounds isolated from Polygonum cuspidatum. Vietnam Journal of Chemistry, 2019, 57(4), 496-499.
- Thi Van Anh Nguyen, Huong Duong Thi Ly, Thi Thom Vu, Thi Thu Nguyen, Hong Luyen Le. Novel finding on anticoagulant activity of Canna warszewiczii extracts. Asian Journal of Pharmacognosy, 2018, 2(2):30-31, 5-10.
- B Cabanillas, P Vásquez-Ocmín, I Zebiri, E Rengifo, M Sauvain, HL Le, A Vaisberg, L Voutquenne-Nazabadioko, Mohamed Haddad. A new 5-alkylresorcinol glucoside derivative from Cybianthus magnus. Natural product research, 2016, 30 (3), 293-298.
- HL Le, V Jullian, C Claparols, M Vansteelandt, M Haddad, C Cabou, Eric Deharo, Nicolas Fabre. Development and validation of liquid chromatography combined with tandem mass spectrometry methods for the quantitation of Simalikalactone E in extracts of Quassia amara L. and in Mouse Blood. Phytochemical Analysis, 2015, 26 (2), 111-118.
- HL Le, V Jullian, G Bourdy, C Girardi, E Deharo, AC Le Lamer, N Fabre. Sensitivity enhancement in LC-ESI-MS method using mobile phase additives to quantify Simalikalactone E. Planta Medica, 2012, 78 (11), 1198-1198.
- N Boussetta, E Vorobiev, LH Le, A Cordin-Falcimaigne, JL Lanoisellé. Application of electrical treatments in alcoholic solvent for polyphenols extraction from grape seeds. LWT-Food Science and Technology, 2012, 46 (1), 127-134.