Dr. Le Hong Luyen

Qualifications

• 2009: Bachelor of Chemical Technology. College of Science, Vietnam national University, Hanoi
• 2011: Master of Chemistry – Durable technology. University of Technologies of Compiegne, France
• 2015: Doctor of Chemistry – Biology – Health. University of Toulouse III, France

Research interests

• Analytical chemistry: LC-MS, GC-MS, UV-Vis, IR
• Chemistry of natural compounds: Extraction and isolation of pure compounds, quantification of bioactive compounds targeting for drug development
• Bioactivities: Anti-platelet aggregation and anticoagulant activity, anti-diabetic and antioxidant effects.

Selected publications

1. Van Anh T. Nguyen, Thanh Hang Nguyen, Kieu Oanh T. Nguyen, Phuong Nhung Nguyen, Hong Luyen Le*. Novel findings on the bioactivities of black ginger of Vietnam and optimization of its extraction using response surface methodology. Chemical Papers, 2024, 78, 5191–5207.
2. Le Hong Luyen*, Nguyen Thi Linh, Le Thi Hong. Chemical composition, antioxidant activity and extraction optimization of Distichochlamys orlowii Vietnam Journal of Science and Technology, 2024.
3. Le Hong Luyen, Nguyen Trang Linh, Nguyen Chi Thanh, Le Thi Van Anh. Evaluation of the nutritional properties and the antioxidant activity of rice bean (Vigna umbellata) seeds collected in Son La province. Vietnam Journal of Biotechnology, 2024, 22(1): 157-168.
4. Thi Van Anh Nguyen*, Thi Minh Hang Nguyen, Hong Luyen Le, Duc Huy Bui. Antithrombotic activity of the steroids and ent-Kaurane diterpenoids from Canna indica Revista Brasileira Pharmacognosia, 2024, 34, 206-211.
5. Le Thanh Huong, Nguyen Thuy Linh, Le Hong Luyen. Antioxidant and cytotoxic activities of Kaempferia parviflora ex. Baker extracts and its isolated compounds. Journal of Medicinal Materials, 2023, 28 (6), 331 – 336.
6. Hong Luyen Le*, Viet Hau Nguyen, Tien Dat Nguyen, Thi Van Anh Nguyen, Dang Huy Le. Potential antiaggregatory and anticoagulant activity of Kaempferia parviflora extracts and its methoxyflavones. Industrial crops and products, 2023, 192, 116030.
7. Thi Van Anh Nguyen, Kieu-Oanh Nguyen Thi, Nhung Phuong Nguyen, Hong Luyen Le*. Antioxidant and antithrombotic activities of the Distichochlamys citrea leaves extract. Vietnam Journal of Biotechnology, 2023, 21: 1-17.
8. Nguyen Xuan Tung, Nguyen Thanh Hai, Le Thi Hong, Nguyen Thi Van Anh, Le Hong Luyen*. Quantification of total polyphenols, total flavonoids and evaluation of antioxidant activity of the aerial part of Distichochlamys orlowii Larsen & M.F. Newman. VNU Journal of Science: Medical and Pharmaceutical Sciences, 2023, 39 (4), 55-63-1.
9. Thi Van Anh Nguyen, Thi Minh Hang Nguyen, Hong Luyen Le & Duc Huy Bui. Potential antithrombotic effect of two new phenylpropanoid sucrose esters and other secondary metabolites of Canna indica L. rhizome. Natural Product Research, 2023, 38:6,897-905.
10. Nguyen Thi Van Anh*, Le Hong Luyen, Pham Viet Ha Quang. Inhibitory effect on human blood coagulation of aerial Canna edulis Ker Gaw Journal of Medicinal Materials, 2023, 28 (6), 385 – 388.
11. Trinh Hoang Nghia, Vu Toan Khanh, Cam Tu Vu, Nguyen Thi Kieu Oanh, Nguyen Thi Van Anh, Le Hong Luyen, Nobuaki Negishi, Sylvain Ouillon and Bui Van Hoi*. Removal of carbamazepine in aqueous solution by TiO2 ceramic photo-catalyst under simulated solar light: Kinetics, effects of environmental factors and degradation pathways. Water, 2023, 15, 1583.
12. Hong Luyen Le, Thi Minh Hang Nguyen, Thi Thom Vu, Thi Tu Oanh Nguyen, Huong Duong Thi Ly, Nguyen Thanh Le, Van Hung Nguyen, Thi Van Anh Nguyen. Potent antiplatelet aggregation, anticoagulant and antioxidant activity of aerial Canna x generalisH Bailey & E.Z Bailey and its phytoconstituents. South African Journal of Botany, 2022, 147, 882 – 893.
13. Le Hong Luyen, Vu Thi Thom, Le Thi Thanh Huong, Duong Thi Ly Huong, Nguyen Thi Van Anh. Inhibitory Effect on Human Platelet Aggregation, Antioxidant Activity, and Phytochemicals of Canna warszewiczii (A. Dietr) Nb. Tanaka. Pharmacognosy Research, 2020, 12, 47-52.
14. Thi Minh Hang Nguyen, Hong Luyen Le, Thi Thoa Ha, Bich Hau Bui, Nguyen Thanh Le, Van Hung Nguyen, Thi Van Anh Nguye Inhibitory effect on human platelet aggregation and coagulation and antioxidant activity of C. edulis Ker Gawl rhizome and its secondary metabolites. Journal of Ethnopharmacology, 2020, 263, 113-136 .
15. Hong-Luyen Le, Dao-Cuong To, Manh-Hung Tran, Thi-Thuy Do, and Phi-Hung Nguyen. Natural PTP1B inhibitors from Polygonum cuspidatum and their 2-NBDG uptake stimulation. Natural Product Communications, 2020, 15(9), 1–7.
16. Le Hong Luyen, Pham Minh Quan, Nguyen Phi Hung. Protein tyrosine phosphatase 1B inhibitory activities of compounds isolated from Polygonum cuspidatum. Vietnam Journal of Chemistry, 2019, 57(4), 496-499.
17. Thi Van Anh Nguyen, Huong Duong Thi Ly, Thi Thom Vu, Thi Thu Nguyen, Hong Luyen Le. Novel finding on anticoagulant activity of Canna warszewiczii Asian Journal of Pharmacognosy, 2018, 2(2):30-31, 5-10.
18. B Cabanillas, P Vásquez-Ocmín, I Zebiri, E Rengifo, M Sauvain, HL Le, A Vaisberg, L Voutquenne-Nazabadioko, Mohamed Haddad. A new 5-alkylresorcinol glucoside derivative from Cybianthus magnus. Natural product research, 2016, 30 (3), 293-298.
19. HL Le, V Jullian, C Claparols, M Vansteelandt, M Haddad, C Cabou, Eric Deharo, Nicolas Fabre. Development and validation of liquid chromatography combined with tandem mass spectrometry methods for the quantitation of Simalikalactone E in extracts of Quassia amara and in Mouse Blood. Phytochemical Analysis, 2015, 26 (2), 111-118.
20. N Boussetta, E Vorobiev, LH Le, A Cordin-Falcimaigne, JL Lanoisellé. Application of electrical treatments in alcoholic solvent for polyphenols extraction from grape seeds. LWT-Food Science and Technology, 2012, 46 (1), 127-134.