Dr. Nguyen Thy Ngoc

Qualifications

• 2010: Engineer in Biotechnology. Hanoi University of Science and Technology
• 2012: Master in Biotechnology. Hanoi University of Science and Technology
• 2016: PhD in Genomic and Bioinformatic. University of Aix – Marseille.

Research interests

• My research mainly focuses on the human genetic variations that are involved in inherited diseases. The overall objective is to identify genes, gene networks and their variations involved in the outcome of human diseases. The technique combines a positional cloning approach in humans, and functional analysis in genetic polymorphisms.

Selected publications

1. The prevalence of JAK2 exon12 mutations in Vietnamese patients with JAK2 V617F-negative polycythemia vera: frequent or rare? Nguyen Thy Ngoc, Nguyen Thuy Linh, Nguyen Thi Xuan. Human Heredity. ISSN: 1423-0062 (2022)
2. JAK2 rs10974944 is associated with both V617F-positive and negative myeloproliferative neoplasms in a Vietnamese population: A potential genetic marker. Nguyen Thy Ngoc, Bui Bich Hau, Nguyen Ba Vuong, Nguyen Thi Xuan. Molecular Genetics & Genomic Medicine. ISSN : 2324-9269 (2022)
3. Prevalence of CYLD mutations in Vietnamese patients with polycythaemia vera. Do Thi Trang, Nguyen Hoang Giang, Bui Kieu Trang, Nguyen Thy Ngoc, Nguyen Van Giang, Nguyen Xuan Canh, Nguyen Ba Vuong, Nguyen Thi Xuan. ADVANCES IN CLINICAL AND EXPERIMENTAL MEDICINE. ISSN : 1899-5276 (2022)
4. Exome sequencing revealed the potential causal mutation in a Vietnamese patient with Apert syndrome. Nguyen Thy Ngoc, Hoang Hai Duc. Gene Reports. ISSN: 2452-0144 (2021)
5. Identification of novel missense mutations associated with non-syndromic syndactyly in two Vietnamese trios by Whole exome sequencing. Nguyen Thy Ngoc, Nguyen Thuy Duong, Do Hai Quynh, Nguyen Dang Ton, Hoang Hai Duc, Le Thi Minh Huong, Luong Thi Lan Anh, Nong Van Hai Clinica Chimica Acta. ISSN : 0009-8981 (2020).
6. Polymorphisms of ABCG2 and SLC22A12 Genes Associated with Gout Risk in  Vietnamese Population. Nguyen Thuy Duong, Nguyen Thy Ngoc, Nguyen Tran Minh Thang, Bach Thi Hoai Phuong, Nguyen Thanh Nga, Nguyen Doan Tinh, Do Hai Quynh, Nguyen Dang Ton, Nong Van Hai. Medicina. ISSN: 1010-660X (2019).
7. Genetic and enzymatic characterization of 3-O-sulfotransferase SNPs associated with Plasmodium falciparum parasitaemia. Thy Ngoc Nguyen, Romain R. Vivès, Magali Torres, Vincent Delauzun, Els Saesen, Véronique Roig-Zamboni, Hugues Lortat-Jacob, Pascal Rihet,Yves Bourne. Glycobiology. ISSN : 0959-6658 (2018).
8. Association of a functional TNF variant with Plasmodium falciparum parasitaemia in a Congolese population. Thy Ngoc Nguyen, Sabrina Baaklini, F Koukouikila, M Ndounga, M Torres, L Pradel, F Ntoumi, P Rihet. Gene and Immunity. ISSN : 1466-4879 (2017).
9. Biochip for Real-Time Monitoring of Hepatitis B Virus (HBV)by Combined Loop-Mediated Isothermal Amplification and Solution-Phase Electrochemical Detection. Bui Quang Tien, Nguyen Thy Ngoc, Nguyen Thai Loc, Vu Thi Thu, Tran Dai Lam. Journal of Electronic Materials. ISSN : 0361-5235 (2017).
10. Beyound genome-wide scan: Association of a cis-regulatory NCR3 variant with mild malaria in a population living in the Republic of Congo. Sabrina Baaklini, Sarwat Afrifi, Thy Ngoc Nguyen, Felix Koukouikila, Mathieu Ndounga, Jean Imbert, Magali Torres, Lydie Pradel, Francine Ntoumi, Pascal Rihet . PLoS One. ISSN : 1932-6203. (2017) 
11. Evaluate the Structural Impact of the Missense Mutation JAK2 V617F in Janus Kinase 2 by Docking Study. Nguyen Thy Ngoc, Bui Bich Hau. VNU Journal of Science: Natural Sciences and Technology. ISSN: 2588-1140 (2022).
12. STUDY ON THE ASSOCIATION OF SLC2A9 rs16890979 WITH GOUT IN 410 VIETNAMESE INDIVIDUALS. Nguyen Tran Minh Thang, Nguyen Thy Ngoc, Nguyen Thanh Nga, Nong Van Hai, Nguyen Thuy Duong. ACADEMIA JOURNAL OF BIOLOGY. ISSN 2615-9023 (2021)
13. ĐÁNH GIÁ MỘT SỐ PHƯƠNG PHÁP XÁC ĐỊNH ĐỘT BIẾN JAK2 V617F PHỤC VỤ VIỆC DỰ ĐOÁN NGUY CƠ MẮC BỆNH ĐA HỒNG CẦU VÀ MỘT SỐ CĂN BỆNH TĂNG SINH TỦY ÁC TÍNH KHÁC.  Nguyễn Thy Ngọc, Bùi Bích Hậu, Phạm Hoàng Nam, Trần Tuấn Anh, Đỗ Thị Trang, Nguyễn Thị Xuân. Journal of Biotechnology. ISSN: 1811-4989 (2021)
14. Khảo sát sự đa dạng di truyền vùng D-loop hệ gen ty thể ở ba nhóm tộc người: Hà Nhì, Phù Lá, Si La. Nguyễn Văn Phòng, Nguyễn Thy Ngọc, Nguyễn Doãn Tình , Nguyễn Thùy Dương, Nông Văn Hải. Tạp chí Khoa học và Công nghệ Việt Nam. ISSN: 2525-2461 (2019)
15. Đa hình vùng D-loop hệ gen ty thể của các cá thể dân tộc Kinh và Mảng cùng trong nhóm ngữ hệ Nam Á. Nguyễn Thy Ngọc, Nguyễn Bảo Trang, Nguyễn Quang Huy, Nguyễn Đăng Tôn, Nguyễn Thùy Dương. Tạp chí Công nghệ sinh học. ISSN: 1811-4989 (2018).
16. Research on the conditions and the production process of biological product BIO-TS3 used for the intensive shrimp farming. Khuat Huu Thanh, Nguyen Thy Ngoc.Tạp chí khoa học Công nghệ các trường đại học Kỹ thuật. ISSN: 0868-3980 (2010).
17. Detection of a Novel Mutation on the Gene ESCO2 in a Pediatric Patient with Syndactyly. Nguyen Thy Ngoc, Le Thi Van Anh, Nguyen Thuy Duong, Nong Van Hai. VNU Journal of Science: Natural Sciences and Technology. ISSN: 2588-1140 (2020).
18. Study on genetic variations of the D-loop region in three Vietnamese ethnic groups Kinh, Lolo and Lahu. Nguyen Thuy Duong, Nguyen Van Phong, Nguyen Thy Ngoc, Nong Van Hai. Journal of Biotechnology. ISSN: 1811-4989 (2020).