Dr. Nguyen Thi Trang Huyen

Qualifications 

• 2006-2011: Bachelor in Biology (specialty in Biochemistry) at Hanoi University of Science, Vietnam National University. 
• 2011-2013: Master in Biotechnology and Pharmacology (specialty in Drug Development) at University of Science and Technology of Hanoi.
• 2015-2017: PhD program (specialty in Oncology and Neuroscience) at University of Aix-Marseille, France 

Research interests

• Isolating and screening bioactive fractions/compounds from Vietnamese plants and marine organisms in collaboration with Institute of Biotechnology 
• Testing bioactive activities and potential effects of fraction/compounds on cell lines (in vitro) and animal (in vivo)
• Investigating potentially molecular mechanisms of bioactive compounds/fractions 
• Studying the molecular mechanism of pathogenesis of some human related diseases such as human liver cancer. 

Selected publications

1. Minh T.H. Nguyen, Quang V. Ngo, Huyen T. T. Nguyen, Quan M. Pham, Trang H. Dinh, Huong T.T. Nguyen, Nguyen V. Tinh, and Phuong T.M. Nguyen. Osteogenic activity of lupeol isolated from Clinacanthus nutans Lindau: acvitity and mode of action. Journal of Chemistry, 2021
2. Huyen T.T. Nguyen, Minh T.H Nguyen, Thu X. Nguyen, Quan M. Pham, Ha X. Nguyen, Phuong T.M. Nguyen. Osteoblastogenic activity of ethyl acetate extract and a major active compound of Smilax glabra Roxb roots. Asian pacific journal of tropical biomedicine, 2021
3. Le Phuong Ha, Nguyen Van Ngoc, Nguyen Thi Trang Huyen, Le Thi Thu Hang, Nguyen Thi Kieu Oanh, Nguyen Thi Mai Phuong, Nguyen Thi Hong Minh. Total phenolic content, flavonoid content and antioxidant activities of tamarind seed extracts, VJS, 2021.
4. J. Guillot, C. Dominici, A. Lucchesi, Huyen T.T. Nguyen, J. Nigri et al,. Sympathetic axonal sprouting induces changes in macrophage populations and protects against pancreatic cancer. Nature communications, 13: 1985 (2022)
5. Huyen T.T. Nguyen, Quang V.Ngo, Duong T.T.Le, Minh T.H.Nguyen, and Phuong T.M. Nguyen. β-sitosterol from Clinacanthus nutans Lindau enhances osteoblastogenic activity via upregulation of differentiation related genes and proteins. Bioscience, Biotechnology, and Biochemistry. 2022. Vol.86, No.12, 1615-1622.
6. Nguyen Dieu Linh, Nguyen Thi Trang Huyen, Nguyen Hai Dang, Benoit Piro, Vu Thi Thu. Electrochemical interface based on polydopamine and gold nanoparticles/reduced graphene oxide for impedimetric detection of lung cancer cells. RSC Adv. 2023, 13, 10082.
7. Nguyet Thi Doan, Hung Minh NGUYEN, Tuyet Loan Thi Bui, Huyen Trang Thi Nguyen, Duong Nguyen, Tru Van Nguyen. Hexane extract of Telosma cordata enhances neurite outgrowth via the epigenetically regulated genes expression in neuronal cells. Notulae Botanicale Horti Agrobotanici CluJ Napoca. Volume 51, Issue 4, 13204.
8. Ngo VQ, Nguyen TMP, Dang VL, Nguyen TTH, Do TTX, Thanh TTT (2023). Xanthine oxidase and nitric oxide inhibitory activities of compounds isolated from Gomphrena celosioides. Vietnam J.Chem, 1-7.
9. Ngo VQ, Nguyen TMP, Dang VL, Do TTX, Phan VK, Nguyen TTH, Thanh TTT (2023). Structure, absolute configuration and cytotoxicity of compounds isolated from Decaschistia harmandii. Vietnam J.Chem, 1-6.
10. Nguyen TMP, Vu TT, Nguyen VT, Nguyen TTH, Nguyen TV, Dang TD, Phung TMP, La DD (2024). Green synthesis of selenium nanoparticles with augmented biological activity using Smilax glabra Roxb extract combined with electrochemical plasma. Nano-Structures & Nano-Objects, volume 38 (101185).